AMICACINA BULA PDF

Antibiotics: therapeutic importance and perspectives for the discovery and development of new agents. There is a continuous need for antibiotics, mainly with new mechanisms of action, since infectious diseases represent the second major cause of death in the world and bacteria resistance levels are high. This review describes the contribution of microbial natural products for the development of the major antibiotic classes, the mechanisms of action of current antibiotics, some modern approaches involving genetic tools for the discovery and development of new antibiotics from microbial products and antibiotics in clinical trials. Keywords: microbial natural products; drug discovery; antibiotics. Figura 1. Figura 2.

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Nas diarreias causadas por Shigella, Salmonella, E. Ariffin H, Arasu A, Mahfuzah M et al: Single-daily ceftriaxone plus amikacin versus thrice-daily ceftazidime plus amikacin as empirical treatment of febrile neutropenia in children with cancer.

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Soteriou M, Recker F, Geroulanos S et al: Perioperative antibiotic prophylaxis in cardiovascular surgery: a prospective randomized comparative trial of cefazolin versus ceftriaxone. World J Surg ; Thomas R, Alvino P, Cortino GR et al: Long-acting versus short-acting cephalosporins for preoperative prophylaxis in breast surgery: a randomized double-blind trial involving 1, patients. Chemotherapy ; Varsano I, Frydman M, Amir J et al: Single intramuscular dose of ceftriaxone as compared to 7-dayamoxicillin therapy for acute otitis media in children.

Obstet Gynecol ; J Chemother ; 12 1

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